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CoQ10 (Co Enzyme Q10)
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Coenzyme Q10 or CoQ10 belongs to a family of substances called ubiquinones. Ubiquinones, are lipophilic, water-insoluble substances involved in electron transport and energy production in mitochondria. Specifically CoQ10 is used by the body to transform food into adenosine triphosphate (ATP), the energy used to power the human body. Nearly, every cell of the human body contains CoQ10. It is concentrated in the mitochondria, the area of cells where energy is produced.
CoQ10 is a powerful antioxidant that protects the body from free radicals and helps preserve vitamin E, the major antioxidant of cell membranes and blood cholesterol. Coenzyme Q10 may also be indicated in cardiovascular disease, particularly in congestive heart failure. It may also be indicated to correct reduced blood levels of CoQ10. It also appears to be useful in managing of periodontal disease in some individuals. There is far less evidence to support claims that it has positive effects in cancer, muscular dystrophy and immune dysfunction.
Dietary CoQ10 is found primarily in fish and meat, but the amounts in food are far less than what can be obtained from supplemental forms.
Adult levels of supplementation are recommended at 30–90 mg per day, although people with specific health conditions may supplement with higher levels (under the supervision of a doctor).
Congestive heart failure patients who are taking CoQ10 should not discontinue taking CoQ10 supplements unless under the supervision of a doctor.
Weber C, Jakobsen TS, Mortensen SA, et al. Antioxidative effect of dietary coenzyme Q10 in human blood plasma. Int J Vitam Nutr Res 1994;64:311-4.
Thomas SR, Neuzil J, Stocker R. Inhibition of LDL oxidation by ubiquinol-10. A protective mechanism for coenzyme Q in atherogenesis? Mol Aspects Med 1997;18:S85-95.
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